Harvard Medical School is under fire from critics for its ties to Big Pharma. While the school tries to sort it all out, two professors battle for its soul.

Brendan Ciecko made his name—and a boatload of money—as the music industry’s go-to website designer. Now that he’s finally old enough to buy beer, he’s decided to take on a slightly less sexy project: remaking his hardscrabble hometown.

Once upon a time, Seth Greenberg reigned over a glittery club scene that upended the bar-hopping habits of stodgy old Boston. Now the prodigal impresario has returned. Can he bring that magic back?